| Villanova at 6 Penn State | 12:00pm | BTN | |
| 2 Georgia at Vanderbilt | 12:00pm | SECN | |
| Boise State at Utah State | 12:00pm | CBS | |
| Texas Tech at Texas | 12:00pm | ABC | |
| Bowling Green at Minnesota | 12:00pm | ESPNU | |
| FIU at Central Michigan | 12:00pm | ESPN+ | |
| Miami (Ohio) at Army | 12:00pm | CBSSN | |
| Missouri at Boston College | 12:00pm | ESPN2 | |
| New Hampshire at Pitt | 12:00pm | ACCNX/ESPN+ | |
| 12 Notre Dame vs. 18 Wisconsin (in Chicago, IL) | 12:00pm | FOX | |
| Ohio at Northwestern | 12:00pm | BTN | |
| Richmond at Virginia Tech | 12:00pm | ACCN | |
| SMU at TCU | 12:00pm | FS1 | |
| LSU at Mississippi State | 12:00pm | ESPN | |
| Wagner at Temple | 12:00pm | ESPN+ | |
| CCSU at 24 Miami (FL) | 12:30pm | RSN/ESPN3 | |
| UMass at 17 Coastal Carolina | 1:00pm | ESPN+ | |
| San Jose State at Western Michigan | 2:00pm | ESPN+ | |
| Texas State at Eastern Michigan | 2:00pm | ESPN+ | |
| Toledo at Ball State | 2:00pm | ESPN+ | |
| Maine at NIU | 2:30pm | ESPN3 | |
| Washington State at Utah | 2:30pm | P12N | |
| 7 Texas A&M vs. 16 Arkansas (in Arlington, TX) | 3:30pm | CBS | |
| 9 Clemson at NC State | 3:30pm | ESPN | |
| Louisville at Florida State | 3:30pm | ESPN2 | |
| 14 Iowa State at Baylor | 3:30pm | FOX | |
| Wyoming at UConn | 3:30pm | CBSSN | |
| UTSA at Memphis | 3:30pm | ESPNU | |
| Towson at San Diego State | 3:30pm | Stadium | |
| Rutgers at 19 Michigan | 3:30pm | ABC | |
| Kent State at Maryland | 3:30pm | BTN | |
| Illinois at Purdue | 3:30pm | BTN | |
| Colorado State at 5 Iowa | 3:30pm | FS1 | |
| Georgia State at 23 Auburn | 4:00pm | SECN | |
| Kansas at Duke | 4:00pm | ACCN | |
| Arkansas State at Tulsa | 5:00pm | ESPN+ | |
| Buffalo at Old Dominion | 6:00pm | ESPN+ | |
| Charleston Sou. at East Carolina | 6:00pm | ESPN+ | |
| Louisiana at Georgia Southern | 6:00pm | ESPN+ | |
| 24 UCLA at Stanford | 6:00pm | P12N | |
| Texas Southern at Rice | 6:30pm | ESPN3 | |
| Navy at Houston | 7:00pm | ESPNU | |
| 25 Kansas State at Oklahoma State | 7:00pm | ESPN+ | |
| North Texas at Louisiana Tech | 7:00pm | Stadium | |
| Tennessee at 11 Florida | 7:00pm | ESPN | |
| Nebraska at 20 Michigan State | 7:00pm | FS1 | |
| Kentucky at South Carolina | 7:00pm | ESPN2 | |
| Akron at 10 Ohio State | 7:30pm | BTN | |
| Southern Miss at 1 Alabama | 7:30pm | SECN | |
| 21 North Carolina at Georgia Tech | 7:30pm | ACCN | |
| West Virginia at 4 Oklahoma | 7:30pm | ABC | |
| Hawaii at New Mexico State | 8:00pm | FloFootball / CW El Paso | |
| Indiana at WKU | 8:00pm | CBSSN | |
| UAB at Tulane | 8:00pm | ESPN+ | |
| Florida Atlantic at Air Force | 8:00pm | FS2 | |
| Troy at ULM | 8:00pm | ESPN+ | |
| New Mexico at UTEP | 9:00pm | ESPN+ | |
| California at Washington | 9:30pm | P12N | |
| USF at 15 BYU | 10:15pm | ESPN2 | |
| Arizona at 4 Oregon | 10:30pm | ESPN | |
| Colorado at Arizona State | 10:30pm | ESPNU | |
| Oregon State at USC | 10:30pm | FS1 | |
